So, the next week will be mid-season finale, similar to seasons 1, 2 and 3. This fits with what the writers/producers have said, that season 5 has two arcs or 'pods' rather than 3 as the last year.
I think that the next episode they will manage to go back to the past, so this will be the end of the first 'pod', which takes place in the future on a Kree-ruled station and the surface of the destroyed Earth with Kasius as the main villain, and then the next 'pod' - which will encompass the rest of season 5 - will be about going back and trying to change the past and break the time loop. Sinara is already dead (I don't see how she could not be, unless the Kree can also resurrect the Kree rather than just humans), and Kasius will probably be killed or otherwise removed as a threat in the mid-season finale, and then maybe the next threat - and probably the Big Bad of the season - will be revealed in a cliffhanger ending. It will certainly have something to do with the "Seer" Kasius is talking about.
I don't know if Franklin Hall will return, it depends on whether they were able to get Ian Hart to return, although Gravitonium is obviously crucial for the story. I hope they at least get David Conrad to come back as Ian Quinn - both because that's a loose end since season 1 (he was one of the show's first villains, worked for Garrett and almost killed Daisy, and had Gravitonium in his possession the last time we saw him, but as far as we know, he is still at large), and to explain how Gravitonium ended up where it ended up.
We're also yet to see a rather publicized announced
guest star whose role everyone has been hush-hush about.